system shock 2 review shock 2 walkthrough

In this narrative review, we highlight how clinicians could improve the use of pathogen-specific and of the most used host-response biomarkers, procalcitonin and C-reactive protein, to improve the clinical care of patients with sepsis. Published data support the use of biomarkers for pathogen identification, clinical diagnosis, and optimization of antibiotic treatment. More than 250 biomarkers have been identified and evaluated over the last few decades, but no biomarker accurately differentiates between sepsis and sepsis-like syndrome. In this context, biomarkers could be considered as indicators of either infection or dysregulated host response or response to treatment and/or aid clinicians to prognosticate patient risk. Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. Intensive Care Medicine volume 49, pages 142–153 ( 2023) Cite this article

How to use biomarkers of infection or sepsis at the bedside: guide to clinicians

System shock 2 review shock 2 walkthrough