Nitro Cloud is compatible with any web browser on any machine. Nitro's desktop products are available on Windows and Mac. This can not only create additional workflow (re-download, re-direct:save) if the document was opened into the reader from an external source - but in some cases (paywall, limited-articles, sign-up/subscribe, etc.) not just inconvenience the user but also impose additional actual costs or restrict access altogether. That's not quite true, as several functions are disabled including a simple of an existing opened document. It was claimed that 'users can get the same functionality with an expired free trial of Nitro PDF Pro'. The company sunset their PDF reader, Nitro Reader, in 2017. Nitro also manages several free document conversion sites. Subscription services include cloud-based user management, deployment and analytics tools. Products include a PDF editor, a browser-based application for electronic signatures and PDF productivity tools. In June 2021, the company purchased PDFPen, a Mac, iPad, and iPhone PDF editing app. In 2018, Nitro PDF Pro was used by more than 650,000 businesses.

In 2018, it launched the Nitro Productivity and eSigning Suite. In 2015, the company reported 1 million licenses sold. Nitro Software was founded in Melbourne, Australia, by a team of three, as an alternative PDF software to Adobe Acrobat. Nitro PDF Pro is an application used to create and edit Portable Document Format (PDF) files and digital documents.

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